Familial risk of early and late onset cancer
نویسندگان
چکیده
منابع مشابه
Familial risk of early and late onset cancer: nationwide prospective cohort study OPEN ACCESS
Objective To determine whether familial risk of cancer is limited to early onset cases. Design Nationwide prospective cohort study. Setting Nationwide Swedish Family-Cancer Database. Participants All Swedes born after 1931 and their biological parents, totalling >12.2 million individuals, including >1.1 million cases of first primary cancer. Main outcome measures Familial risks of the concordan...
متن کاملFamilial risk of early and late onset cancer: nationwide prospective cohort study
OBJECTIVE To determine whether familial risk of cancer is limited to early onset cases. DESIGN Nationwide prospective cohort study. SETTING Nationwide Swedish Family-Cancer Database. PARTICIPANTS All Swedes born after 1931 and their biological parents, totalling >12.2 million individuals, including >1.1 million cases of first primary cancer. MAIN OUTCOME MEASURES Familial risks of the c...
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CONTEXT It is unclear whether late-onset Parkinson disease (PD), which is the most typical and most common form of the disease, has a familial component. Evidence for familial aggregation is key to whether research should focus on gene discovery or search for environmental factors. OBJECTIVE To investigate familial aggregation of early-onset and late-onset PD separately. METHODS Using survi...
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Recent admixture mapping and linkage/association studies have implicated an approximately 1 Mb region on chromosome 8q24 in prostate cancer susceptibility. In a subsequent follow-up investigation, Haiman et al. (Nat Genet 2007;39:638-44) observed significant, independent associations between 7 markers within this region and sporadic prostate cancer risk in a multi-ethnic sample. To clarify the ...
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ژورنال
عنوان ژورنال: The Journal of the Royal College of Physicians of Edinburgh
سال: 2013
ISSN: 1478-2715,2042-8189
DOI: 10.4997/jrcpe.2013.209